My physican prescribed Bydureon which comes in an injectible pen 4 per box. Upon using one pen would not work. It plugged and would not inject. I contacted the pharmacy who told me to call the manufacturer. The manufacturer told me they couldn’t help. These cost taxpayers $700 a box (medicare part d). When I need a refil I’m always out before the insurance will pay for another refil due to defective product.